Precursor N-cadherin mediates glial cell line-derived neurotrophic factor-promoted human malignant glioma

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Precursor N-cadherin mediates glial cell line-derived neurotrophic factor-promoted human malignant glioma

As the most prevalent primary brain tumor, gliomas are highly metastatic, invasive and are characteristic of high levels of glial cell-line derived neurotrophic factor (GDNF). GDNF is an important factor for invasive glioma cell growth; however, the underlying mechanism involved is unclear. In this study, we affirm a significantly higher expression of the precursor of N-cadherin (proN-cadherin)...

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the effects of progesterone on glial cell line-derived neurotrophic factor secretion from c6 glioma cells

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ژورنال

عنوان ژورنال: Oncotarget

سال: 2017

ISSN: 1949-2553

DOI: 10.18632/oncotarget.15302